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"Our admixture dating analysis points to events far back in time, suggesting a more heterogeneous spread of pastoralism and food production in the Sahara compared to Morocco and East Africa"
Generally speaking, people move around and are promiscuous. Staying isolated for that long implies a physical barrier, because cultures generally don't survive for 40,000 years. But an isolated population means genetic issues - but if the population is big then they should have spread at least somewhat.