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Source:https://github.com/SoraKumo001/next-streaming

⬅️ EpiPen For Heart Attacks? Idorsia Launches Phase III Study Of Selatogrel (2021)
epcoa 32 daysReload
This title appears to be confusing based on a comment: Selatogrel has nothing to do with epinephrine from a pharmacological standpoint. It acts more like a super potent quick acting (and deactivating), less blunt aspirin, an anti-platelet / anti clotting drug. The comparison to epipen is just the physical delivery.

Epinephrine is not used for heart attacks (MI) directly, but can be used for cardiac arrest.


carbocation 32 daysReload
The phrase "auto injector" would have been a much more helpful substitute for "EpiPen" here.

> Selatogrel is a P2Y12 receptor antagonist

So this is basically like chewing on ticag, but faster.[1]

1 = https://jamanetwork.com/journals/jamacardiology/fullarticle/...


caycep 31 daysReload
these antiplatelets help a little bit w/ overall risk reduction after a heart attack, I'd say, but the big game changer would be a clot buster like an injectable version of alteplase/tenecteplase or something like that. The caveat is that the better it is at reversing clots, the higher risk of hemorrhage; alteplase/tenecteplase is typically given in a critical care/emergency Dept setting w/ surgery/intensivists hovering over the patient...

binarymax 32 daysReload
Here’s the ongoing trial info: https://clinicaltrials.gov/study/NCT04957719

pipes 31 daysReload
I've recently started keeping aspirin in my pockets because I've been getting unexplained horrible chest pain issues. I'm only in my forties.